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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9577 | HCV-IN-31 | HCV Protease | |
HCV-IN-31 is a HCV inhibitor with an EC50/EC95 of 15.7 μM. | |||
T15573 | Inarigivir soproxil | SB9200 | HCV Protease |
Inarigivir soproxil (SB9200) is an agonist of innate immunity. It also displays effective antiviral activity against resistant hepatitis C virus (HCV) variants (EC50s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype ... | |||
T6229 | Daclatasvir | Daklinza,EBP 883,BMS-790052 | HCV Protease |
Daclatasvir (EBP 883) (BMS-790052) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture. Phase 3. | |||
T1786 | Daclatasvir dihydrochloride | BMS-790052 dihydrochloride | HCV Protease |
Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is an orally available antiviral agent that inhibits the NS5A region of the hepatitis C virus (HCV) and is used in combination with other oral antiviral agents to ... | |||
T22142 | RO8191 | RO4948191,CDM-3008 | HCV Protease , HBV , JAK , IFNAR , STAT |
RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor. | |||
TQ0162 | R-1479 | 4'-Azidocytidine | HCV Protease |
R-1479 (4'-Azidocytidine) is an RdRp inhibitor with an IC50 value of 1.28 μM for HCV RNA replication in the HCV subgenomic replicon system. | |||
T16088 | MK-0608 | HCV Protease | |
MK-0608 is an orally bioavailable HCV replication inhibitor in vitro(EC50 = 0.3 μM and EC90=1.3 μM in the subgenomic-replicon assay). | |||
T9249 | ITMN4077 | Antiviral | |
ITMN4077 has antiviral activity against Hepatitis C virus infected in human HuH7 cells assessed as inhibition of HCV subgenomic replicon replication with an EC50 of 2.131μM. | |||
T4988 | Boceprevir | SCH 503034,EBP 520 | HCV Protease , SARS-CoV |
Boceprevir (SCH 503034) is a novel, potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with Ki of 14 nM in both enzyme assay and EC90 of 350 nM in cell-based replicon assay. | |||
T6729 | Lomibuvir | VX-222,VCH-222 | HCV Protease |
Lomibuvir (VCH-222) (VX-222) is a selective, non-nucleoside allosteric inhibitor of HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC 50 of 5.2 nM. Lomibuvir... | |||
T3334 | Velpatasvir | GS-5816 | HCV Protease , SARS-CoV |
Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. GS-5816 has demonstrated pan-genotypic activity and a high barrier to resistance in HCV replicon assays. GS-5816 d... | |||
T60531 | 2'-C-Methyladenosine | HCV Protease | |
2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication and a ribonucleoside diphosphate reductase inhibitor from Corynebacterium renalis.2'-C-Methyladenosine inhibits HCV replicon and NS5B-catalyzed ... | |||
T7215 | NM107 | NM-107,2'-C-Methylcytidine | HCV Protease |
NM107 (2'-C-Methylcytidine) is a ribonucleoside with broad-spectrum antiviral activity, is an nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase, NM 107 in the wild-type replicon cells with the EC50 of 1... | |||
T38237 | 2′-O-Methylcytidine | Nucleoside Antimetabolite/Analog , HCV Protease | |
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replication in a replicon assay (IC50= 21.2 μM). 1.Migliaccio, G.... | |||
T12954 | Sofosbuvir 13CD3 | GS-7977 13CD3,PSI-7977 13CD3 | Others |
Sofosbuvir 13CD3 is the deuterium labeled Sofosbuvir. Sofosbuvir is an active HCV RNA replication inhibitor in the HCV replicon assay, with potent anti-hepatitis C virus (HCV) activity. | |||
T12958 | Sofosbuvir impurity C | Others | |
Sofosbuvir impurity C is the less active impurity of Sofosbuvir. Sofosbuvir is an active HCV RNA replication inhibitor in the HCV replicon assay,with potent anti-hepatitis C virus (HCV) activity. | |||
T12959 | Sofosbuvir impurity D | Others | |
Sofosbuvir impurity D is the less active impurity of Sofosbuvir. Sofosbuvir is an active HCV RNA replication inhibitor in the HCV replicon assay,with potent anti-hepatitis C virus (HCV) activity. | |||
T64202 | HCV-IN-40 | ||
HCV-IN-39 (Compound 18a) is a potent, orally active nucleoside inhibitor of hepatitis C virus (HCV) that acts on the GT1a replicon (EC50: 0.259 μM), GT1b replicon (EC50: 0.434 μM) and GT1b CES1 replicon (EC50. 0.069 μM). | |||
T15631 | JTK-853 | Others | |
JTK-853 is a novel, non-nucleoside inhibitor of Hepatitis C Virus (HCV) polymerase. It also displays effective antiviral activity in HCV replicon cells (EC50s: 0.38 and 0.035 µM in genotype 1a H77 and 1b Con1 strains, re... | |||
T12955 | Sofosbuvir D6 | PSI-7977 D6,GS-7977 D6 | Others |
Sofosbuvir D6 is the deuterium labeled Sofosbuvir. Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity. |